Leukemic Mantle Cell Lymphoma: Clinical and Pathologic Spectrum of Twenty-Three Cases

@article{Schlette2001LeukemicMC,
  title={Leukemic Mantle Cell Lymphoma: Clinical and Pathologic Spectrum of Twenty-Three Cases},
  author={Ellen Schlette and Raymond Lai and Mihaela M Onciu and Dorota D Doherty and Carlos E Bueso-Ramos and L Jeffrey Medeiros},
  journal={Modern Pathology},
  year={2001},
  volume={14},
  pages={1133-1140}
}
Twenty-three patients with marked leukemic involvement by mantle cell lymphoma (MCL) are described. Each patient had an absolute lymphocyte count more than 10 × 109/L. The diagnosis of MCL was supported by compatible immunophenotypic findings and the t(11;14)(q13;q32) in all cases. Morphologically, these cases exhibited a spectrum of findings that we divided into two groups using a cutoff of 20% large or blastoid cells (log rank test, P = .004). Patients with small-cell (<20%) morphologic… CONTINUE READING
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BCL - 1 rearrangements and p 53 mutations in atypical chronic lymphocytic leukemia with t ( 11 ; 14 ) ( q 13 ; q 32 )

  • C DeAngeli, D Gandini, A Cuneo, S Moretti, R Bigoni
  • Haematologica
  • 2000

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