Leukemia-derived dendritic cells in acute myeloid leukemia exhibit potent migratory capacity

@article{Westers2005LeukemiaderivedDC,
  title={Leukemia-derived dendritic cells in acute myeloid leukemia exhibit potent migratory capacity},
  author={Theresia M. Westers and Ilse Houtenbos and N C L Snoijs and A A van de Loosdrecht and Gert Jan Ossenkoppele},
  journal={Leukemia},
  year={2005},
  volume={19},
  pages={1270-1272}
}
A majority of acute myeloid leukemia (AML) patients in complete remission will eventually relapse due to persistence of minimal residual disease (MRD). Development of alternative therapeutic approaches to prevent relapse is a great challenge. Dendritic cell (DC)-based immunotherapy targeting residual leukemic cells might offer an interesting adjuvant therapy. Effective induction of antileukemia responses in vivo requires DCs with high expression levels of costimulatory molecules, capacity to… CONTINUE READING