Leukemia cells directly phagocytose blood cells in AML-associated hemophagocytic lymphohistiocytosis: a case report and review of the literature.

@article{Hatano2015LeukemiaCD,
  title={Leukemia cells directly phagocytose blood cells in AML-associated hemophagocytic lymphohistiocytosis: a case report and review of the literature.},
  author={Kaoru Hatano and Tadashi Nagai and Tomohiro Matsuyama and Yu Sakaguchi and Shin-ichiro Fujiwara and Iekuni Oh and Kazuo Muroi and Keiya Ozawa},
  journal={Acta haematologica},
  year={2015},
  volume={133 1},
  pages={98-100}
}
A 64-year-old man was admitted to our hospital with a 3-day history of high fever and oral bleeding. Hematological examination revealed pancytopenia: his white blood cell count was 0.7 × 10 9 /l with 39% monocytoid blasts, hemoglobin 9.6 g/dl and a platelet count of 21 × 10 9 /l. Bone marrow aspiration disclosed hypocellular bone marrow with 77.2% monocytoid blasts ( fig. 1 a). The blasts were positive for CD13, CD33, CD56, CD15, CD36, CD34 and CD14, but negative for myeloperoxidase on flow… CONTINUE READING