Leukemia-associated antigens detected by a nonhuman primate antiserum to a Ph1+ myeologenous leukemia cell line.

@article{Lozzio1977LeukemiaassociatedAD,
  title={Leukemia-associated antigens detected by a nonhuman primate antiserum to a Ph1+ myeologenous leukemia cell line.},
  author={B. B. Lozzio and Carmen B. de Lozzio and S. Krauss and Carl J. Wust and Anthony J. Girardi},
  journal={Blood},
  year={1977},
  volume={50 1},
  pages={115-24}
}
Blood, Vol. 50, No. 1 (July), 1977 115 The specificity of an antiserum (titer 1:500) raised in a monkey against K-562 undifferentiated cells with the Philadelphia chromosome (Ph’) was determined. Antibody-dependent, complement-mediated cytotoxicity was demonstrated for both bone marrow cells and peripheral leukocytes from patients with myelogenous and lymphatic leukemias, but not for mature normal hematopoietic cells and those from patients with leukemia in remission. A monospecific antiserum… CONTINUE READING

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