Leukemia Inhibitory Factor Enhances Endometrial Stromal Cell Decidualization in Humans and Mice

Abstract

Adequate differentiation or decidualization of endometrial stromal cells (ESC) is critical for successful pregnancy in humans and rodents. Here, we investigated the role of leukemia inhibitory factor (LIF) in human and murine decidualization. Ex vivo human (H) ESC decidualization was induced by estrogen (E, 10(-8) M) plus medroxyprogesterone acetate (MPA… (More)
DOI: 10.1371/journal.pone.0025288

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