Leukaemia inhibitory factor or related factors promote the differentiation of neuronal and astrocytic precursors within the developing murine spinal cord.

@article{Richards1996LeukaemiaIF,
  title={Leukaemia inhibitory factor or related factors promote the differentiation of neuronal and astrocytic precursors within the developing murine spinal cord.},
  author={Linda J. Richards and Trevor J. Kilpatrick and Richard P. Dutton and S. S. Tan and David P. Gearing and Perry F. Bartlett and Mark B. Murphy},
  journal={The European journal of neuroscience},
  year={1996},
  volume={8 2},
  pages={
          291-9
        }
}
Previously we have shown that leukaemia inhibitory factor (LIF) potentiates the development of murine spinal cord neurons in vitro, suggesting that it, or related factors, may play an important regulatory role in neuronal development. We have further investigated this role and show here that the generation of neurons in cultures of embryonic day 10 spinal cord cells is inhibited by antibodies to the beta subunit of the LIF receptor. Since there are more undifferentiated precursors in antibody… CONTINUE READING

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