Leucocyte-dependent platelet activation: an alternative pathway for initiation of blood clotting in inflammation

Abstract

Fibrin deposition is a prominent feature of several inflammatory diseases but the extract mechanism(s) leading to fibrinogen-fibrin conversion has not been completely clarified. We describe here a new cellular pathway for initiation of blood clotting resulting from a leucocyte-platelet interaction. Human washed platelet suspensions, free of leucocytes… (More)
DOI: 10.1007/BF01978736

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