Leucine zipper structure of the protein CRE-BP1 binding to the cyclic AMP response element in brain.

@article{Maekawa1989LeucineZS,
  title={Leucine zipper structure of the protein CRE-BP1 binding to the cyclic AMP response element in brain.},
  author={Toshio Maekawa and Hiroshi Sakura and Chie Kanei-Ishii and Tatsuhiko Sudo and Teizo Yoshimura and Jun-ichi Fujisawa and Michiteru Yoshida and Satoshi Ishii},
  journal={The EMBO journal},
  year={1989},
  volume={8 7},
  pages={2023-8}
}
By screening a lambda gt11 library with the multimerized sequence of the cAMP response element (CRE), we isolated human clones encoding the CRE binding protein, CRE-BP1, from a human brain cDNA library. CRE-BP1 expressed in Escherichia coli bound not only to the CRE element of the somatostatin and fibronectin genes, but also to the CRE element of the adenovirus E4 gene, suggesting that the protein was not distinguishable from the adenovirus transcription factor, ATF. The human CRE-BP1 clone… CONTINUE READING

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