Leucine-rich diet supplementation modulates foetal muscle protein metabolism impaired by Walker-256 tumour

@inproceedings{Cruz2014LeucinerichDS,
  title={Leucine-rich diet supplementation modulates foetal muscle protein metabolism impaired by Walker-256 tumour},
  author={Bread Leandro Gomes Cruz and Maria Cristina Cintra Gomes-Marcondes},
  booktitle={Reproductive biology and endocrinology : RB&E},
  year={2014}
}
BACKGROUND Cancer-cachexia induces a variety of metabolic disorders of protein turnover and is more pronounced when associated with pregnancy. Tumour-bearing pregnant rats have impaired protein balance, which decreases protein synthesis and increases muscle breakdown. Because branched-chain amino acids, especially leucine, stimulate protein synthesis, we investigated the effect of a leucine-rich diet on protein metabolism in the foetal gastrocnemius muscles of tumour-bearing pregnant rats… CONTINUE READING