Leucine repeats and an adjacent DNA binding domain mediate the formation of functional cFos-cJun heterodimers.

Abstract

The discovery that the AP-1 family of enhancer binding factors includes a complex of the cellular Fos (cFos) and cellular Jun (cJun) proteins established a direct and important link between oncogenesis and transcriptional regulation. Homodimeric cJun protein synthesized in vitro is capable of binding selectively to AP-1 recognition sites, whereas the cFos… (More)

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Cite this paper

@article{Turner1989LeucineRA, title={Leucine repeats and an adjacent DNA binding domain mediate the formation of functional cFos-cJun heterodimers.}, author={R. Turner and Robert Tjian}, journal={Science}, year={1989}, volume={243 4899}, pages={1689-94} }