LeuO antagonizes H-NS and StpA-dependent repression in Salmonella enterica ompS1.

@article{Cruz2007LeuOAH,
  title={LeuO antagonizes H-NS and StpA-dependent repression in Salmonella enterica ompS1.},
  author={Miguel Angel De la Cruz and Marcos Fern{\'a}ndez-Mora and Carmen Guadarrama and Mario Alberto Flores-Valdez and V{\'i}ctor H Bustamante and Alejandra Mateo V{\'a}zquez and E. Barrera Calva},
  journal={Molecular microbiology},
  year={2007},
  volume={66 3},
  pages={727-43}
}
The ompS1 gene encodes a quiescent porin in Salmonella enterica. We analysed the effects of H-NS and StpA, a paralogue of H-NS, on ompS1 expression. In an hns single mutant expression was derepressed but did not reach the maximum level. Expression in an stpA single mutant showed the same low repressed level as the wild type. In contrast, in an hns stpA background, OmpS1 became abundant in the outer membrane. The expression of ompS1 was positively regulated by LeuO, a LysR-type quiescent… CONTINUE READING

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