Letharia vulpina, a vulpinic acid containing lichen, targets cell membrane and cell division processes in methicillin-resistant Staphylococcus aureus.

@article{Shrestha2016LethariaVA,
  title={Letharia vulpina, a vulpinic acid containing lichen, targets cell membrane and cell division processes in methicillin-resistant Staphylococcus aureus.},
  author={Gajendra Shrestha and Andrew Thompson and Richard A. Robison and Larry L. St. Clair},
  journal={Pharmaceutical biology},
  year={2016},
  volume={54 3},
  pages={413-8}
}
CONTEXT Antibiotic resistance in humans is a major concern. Drugs that target traditional sites and pathways are becoming obsolete; thus, compounds affecting novel targets are needed. Screening lichen metabolites for antimicrobials has yielded promising antimicrobial compounds, yet their mode of action is poorly understood. Letharia vulpina (L.) Hue (Parmeliaceae) has traditionally been used to poison predators, and treat stomach disorders; more recently L. vulpina extracts have demonstrated… CONTINUE READING

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