Lethality of tyrosine in mice

@article{David2004LethalityOT,
  title={Lethality of tyrosine in mice},
  author={John C. David},
  journal={Naunyn-Schmiedeberg's Archives of Pharmacology},
  year={2004},
  volume={293},
  pages={15-23}
}
  • J. C. David
  • Published 2004
  • Chemistry, Medicine
  • Naunyn-Schmiedeberg's Archives of Pharmacology
SummaryHigh doses of tyrosine were found to be lethal in mice. The lethality was potentiated by decarboxylase inhibitors which acted by elevating tissues tyrosine levels when given together with large amounts of tyrosine. The lethality of either tyrosine or tyrosine given in combination with decarboxylase inhibitors was found to be correlated with the elevation of tyrosine levels in liver. This toxicity does not appear to involve either tyramine or p-hydroxyphenylpyruvic acid formation… Expand
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  • Biology, Medicine
  • Naunyn-Schmiedeberg's Archives of Pharmacology
  • 2004
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  • Chemistry, Medicine
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