Lethal weapons: DAP-kinase, autophagy and cell death: DAP-kinase regulates autophagy.


Recently, DAP-kinase was identified as one of the essential regulators of autophagy, activated by signals such as cytokines and ER stress. DAP-kinase is a tumor suppressor that mediates several cell death pathways, such as apoptosis and programmed necrosis. Likewise, functional studies suggest that DAP-kinase may direct autophagy specifically towards… (More)
DOI: 10.1016/j.ceb.2009.11.004

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