Lethal genes in inbred lines

Abstract

IsoLATED lethal mutants are of course rapidly eliminated from inbred lines but pairs of completely linked recessive lethal genes lying opposed on homologous chromosomes are able to balance each other and enforce heterozygosity at these as well as at other loci with which they are completely linked. Inbreeding will preserve such balanced lethal systems and… (More)
DOI: 10.1038/hdy.1956.23

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