Lethal factors and enzymes in the secretion from Duvernoy's gland of three colubrid snakes.

@article{Rosenberg1985LethalFA,
  title={Lethal factors and enzymes in the secretion from Duvernoy's gland of three colubrid snakes.},
  author={Herbert I Rosenberg and Avner Bdolah and Elazar Kochva},
  journal={The Journal of experimental zoology},
  year={1985},
  volume={233 1},
  pages={5-14}
}
Secretion from Duvernoy's gland of the colubrid snakes Malpolon, Spalerosophis, and Thamnophis was obtained by pilocarpine stimulation and tested for lethality and selected enzymatic activities. Pools of secretion from Malpolon and Spalerosophis were fractionated by gel filtration, and several major active fractions were examined. The secretion from Malpolon had an LD50 of 6.5 micrograms/gm in mice; two lethal fractions with LD50's of 2.75 micrograms/gm and 4.5 micrograms/gm were isolated. One… CONTINUE READING