Lethal effects of reserpine plus physostigmine and neostigmine in mice.

@article{Janowsky1976LethalEO,
  title={Lethal effects of reserpine plus physostigmine and neostigmine in mice.},
  author={David S. Janowsky and Robert N Pechnick and E C Janowsky},
  journal={Clinical and experimental pharmacology & physiology},
  year={1976},
  volume={3 5},
  pages={483-6}
}
1. The interaction between the reversible cholinesterase inhibitors, physostigmine and neostigmine and reserpine was studied. 2. A combination of reserpine plus a cholinesterase inhibitor significantly increased lethality in adult male Swiss-Webster mice above that caused by either neostigmine, physostigmine, or reserpine alone. 3. Methscopolamine… CONTINUE READING