Lethal effect and apoptotic DNA fragmentation in response of D-GalN-treated mice to bacterial LPS can be suppressed by pre-exposure to minute amount of bacterial LPS: dual role of TNF receptor 1.

Abstract

AIM To investigate whether induction of tolerance of mice to lipopolysaccharide (LPS) was able to inhibit apoptotic reaction in terms of characteristic DNA fragmentation and protect mice from lethal effect. METHODS Experimental groups of mice were pretreated with non-lethal amount of LPS (0.05 microg). Both control and experimental groups simultaneously… (More)

Topics

Cite this paper

@article{Zhou2005LethalEA, title={Lethal effect and apoptotic DNA fragmentation in response of D-GalN-treated mice to bacterial LPS can be suppressed by pre-exposure to minute amount of bacterial LPS: dual role of TNF receptor 1.}, author={Bing-Rong Zhou and Marina Gumenscheimer and Marina-A Freudenberg and Chris Galanos}, journal={World journal of gastroenterology}, year={2005}, volume={11 22}, pages={3398-404} }