Let-7b inhibits the malignant behavior of glioma cells and glioma stem-like cells via downregulation of E2F2


Glioblastoma multiforme (GBM), the most common and lethal primary brain tumor in adults characterized by high proliferative ability and mortality rate, contains a small subpopulation of cancer stem-like cells (CSCs), which is responsible for GBM progression and therapeutic resistance. Numerous microRNAs are strongly implicated in the malignancy of glioma… (More)
DOI: 10.1007/s13105-016-0512-6


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