Let-7a microRNA suppresses therapeutics-induced cancer cell death by targeting caspase-3

Abstract

MicroRNAs (miRNA) are endogenously expressed non-coding RNAs that regulate gene expression post-transcriptionally. Let-7a miRNA is a founding member in the let-7 family and its down-regulation in association with over-expression of RAS and HMGA2 oncogenes has previously been reported. In the present study, caspase-3, the executioner caspase, was confirmed… (More)
DOI: 10.1007/s10495-008-0256-z

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@article{Tsang2008Let7aMS, title={Let-7a microRNA suppresses therapeutics-induced cancer cell death by targeting caspase-3}, author={Wing Pui Tsang and Tim Tak Kwok}, journal={Apoptosis}, year={2008}, volume={13}, pages={1215-1222} }