Let-7-mediated suppression of mucin 1 expression in the mouse uterus during embryo implantation

@inproceedings{Inyawilert2015Let7mediatedSO,
  title={Let-7-mediated suppression of mucin 1 expression in the mouse uterus during embryo implantation},
  author={Wilasinee Inyawilert and Tzu-Yen Fu and Chun Ting Lin and Pin-Chi Tang},
  booktitle={The Journal of reproduction and development},
  year={2015}
}
Mucin 1 (Muc1) is an integral transmembrane mucin glycoprotein expressed on the apical surface of most epithelia. It is considered to be a barrier to the regulation of embryo implantation by inhibiting attachment of the embryo to the endometrium. Therefore, loss of Muc1 on the surface of uterine epithelial cells is necessary for embryo implantation. Studies have demonstrated that microRNAs (miRNAs) play a key role in enhancing embryo implantation in mammals. In this study, we investigated the… CONTINUE READING

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