Lessons on immune tolerance from the monogenic disease APS1.

Abstract

Autoimmunity is a complex disease process that results from a breakdown in the ability of the immune system to discriminate self from non-self. One approach to unraveling how autoimmunity occurs is to study monogenic diseases, for which a single gene defect is responsible. Recent work on the monogenic autoimmune disease 'autoimmune polyglandular syndrome… (More)

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Cite this paper

@article{Devoss2007LessonsOI, title={Lessons on immune tolerance from the monogenic disease APS1.}, author={Jason J Devoss and Mark S. Anderson}, journal={Current opinion in genetics & development}, year={2007}, volume={17 3}, pages={193-200} }