Lessons learnt from the implementation of maternal immunization programs in England

@article{Amirthalingam2016LessonsLF,
  title={Lessons learnt from the implementation of maternal immunization programs in England},
  author={Gayatri Amirthalingam and Louise H Letley and Harry Campbell and David Green and Joanne Yarwood and M. Ramsay},
  journal={Human Vaccines \& Immunotherapeutics},
  year={2016},
  volume={12},
  pages={2934 - 2939}
}
Maternal immunization is increasingly being recognized as an important platform for the prevention of severe maternal and infant morbidity and mortality from vaccine preventable diseases. Since the 1980s, the widespread use of tetanus toxoid vaccines for pregnant women in developing countries has had a major impact on the burden of neonatal tetanus, with WHO estimating a 94% global reduction in newborn tetanus deaths. More recently, many developed countries have recommended influenza and… 
Key considerations for successful implementation of maternal immunization programs in low and middle income countries
ABSTRACT The Maternal Neonatal Tetanus Elimination program is proof of concept for the feasibility and potential for maternal immunization to reduce neonatal mortality particularly in low and
Factors associated with uptake of influenza and pertussis vaccines among pregnant women in South Australia
TLDR
High uptake of influenza and pertussis vaccines during pregnancy can be attained with health care provider recommendation and inclusion of maternal immunization as part of standard antenatal care.
Protecting newborns from pertussis: The role of partner vaccination in the era of maternal immunization.
TLDR
The majority of mothers and partners reported pertussis vaccination in accordance with recommended guidelines, but concerningly nearly a quarter of newborns were discharged to a home where neither parent was vaccinated, suggesting Cocooning remains an important approach to protect newborns of mothers vaccinated late or not vaccinated in pregnancy.
Prevention of neonatal whooping cough in England: The essential role of the midwife
TLDR
Pregnant women should discuss pertussis immunisation with pregnant women and either signpost them to their GP to receive it or, if commissioned to do so, administer the vaccine themselves.
Efficacy and safety of influenza vaccination during pregnancy: realizing the potential of maternal influenza immunization
TLDR
Experimental and observational evidence support the efficacy, effectiveness and safety of influenza immunization during pregnancy, and these data support the continued provision of inactivated influenza vaccine to pregnant women, as recommended by global immunization policies.
Routine maternal immunization against seasonal influenza, pertussis and tetanus protects the mother, fetus and young infant
Routine maternal immunization against seasonal influenza and pertussis (or tetanus in countries where maternal and neonatal tetanus is a public health concern), is recommended by the WHO and national
Safety and effectiveness of acellular pertussis vaccination during pregnancy: a systematic review
TLDR
Although an increased risk for a diagnosis of fever and chorioamnionitis was detected in pregnant women after pertussis vaccination, there was no association with a higher frequency of clinically relevant sequelae and overall positive benefit-risk ratio.
Enablers and barriers of maternal and neonatal immunization programs in Latin America.
TLDR
There is a need to focus on improving the "immunization journey" for pregnant women through providing more clear and timely information to users and providers; removing barriers to access; ensuring adequate supply, human resources and infrastructure; making the health service experience positive; and establishing integrated information systems that allow for monitoring the progress toward achieving MNI goals.
Barriers and facilitators regarding influenza and pertussis maternal vaccination uptake: A multi-center survey of pregnant women in Italy.
TLDR
Lack of immunization advice by health-care providers and safety concerns were the main vaccination barriers against influenza and pertussis, among surveyed pregnant women, and vaccine delivery in the antenatal care setting could lead to increase of vaccine acceptance among pregnant women.
Vaccination in pregnancy: Challenges and evidence-based solutions.
TLDR
Vaccination in pregnancy (VIP) is dually beneficial - it protects the mother and the baby from tetanus, influenza, and pertussis and requires embedded continuous quality improvement to ensure sustainability.
...
1
2
3
...

References

SHOWING 1-10 OF 58 REFERENCES
Maternal immunization in Argentina: A storyline from the prospective of a middle income country.
TLDR
The importance of vaccination during pregnancy lies not only in directly protecting vaccinated women, but also by indirectly protecting small infants during the first few months of life, in the context of transitioning from child vaccination to family vaccination.
Attitudes to immunisation in pregnancy among women in the UK targeted by such programmes
TLDR
Vaccines in pregnancy can minimise diseases with associated high morbidity and mortality in pregnant women, their unborn and newly born infants and health professionals, midwives in particular, are pivotal in informing women about vaccines.
Effectiveness of maternal pertussis vaccination in England: an observational study
TLDR
The assessment of the programme of pertussis vaccination in pregnancy in England is consistent with high vaccine effectiveness, which probably results from protection of infants by both passive antibodies and reduced maternal exposure, and will provide valuable information to international policy makers.
A case-control study to estimate the effectiveness of maternal pertussis vaccination in protecting newborn infants in England and Wales, 2012-2013.
TLDR
Maternal pertussis vaccination is effective in preventing pertussedis infection in infants aged <8 weeks and may be considered in other countries experiencing high levels of pertussIS notifications.
Pertussis vaccine uptake during pregnancy: we need to do better in the U.S.
TLDR
This report covers the time period before andafter the 2010 pregnancy Tdap recommendations in California (California Department of Public Health, 2010) and the 2011 U.S. Advisory Committee on Immunization Practices (ACIP) recommendations (Centers for Disease Control, Prevention, 2011).
Influenza vaccine given to pregnant women reduces hospitalization due to influenza in their infants.
TLDR
The effectiveness of influenza vaccine given to mothers during pregnancy in preventing hospitalization among their infants, adjusted for potential confounders, was 91.5%, higher than the unadjusted effectiveness for infants aged <6 months.
Pertussis and Influenza Vaccination Among Insured Pregnant Women — Wisconsin, 2013–2014
TLDR
Tdap vaccination among pregnant women increased but plateaued at rates similar to influenza vaccination rates, and prenatal care providers should implement, evaluate, and improve Tdap and influenza vaccination programs, and strongly recommend that pregnant patients receive these vaccines.
Impact of maternal immunization on influenza hospitalizations in infants.
TLDR
The results support the current influenza vaccination recommendation for pregnant women and suggest that infants of vaccinated mothers were 45-48% less likely to have influenza hospitalizations than infants of unvaccinated mothers.
Safety of pertussis vaccination in pregnant women in UK: observational study
TLDR
In women given pertussis vaccination in the third trimester, there is no evidence of an increased risk of any of an extensive predefined list of adverse events related to pregnancy, including stillbirth.
Influenza Vaccination During Pregnancy: Influenza Seasons 2002-2012, Vaccine Safety Datalink.
TLDR
Influenza vaccination coverage among pregnant women increased between the 2002-2003 and 2011-2012 seasons, although it was still below the developmental Healthy People 2020 goal of 80%.
...
1
2
3
4
5
...