Lessons from the neuropathology of atypical forms of multiple sclerosis

  title={Lessons from the neuropathology of atypical forms of multiple sclerosis},
  author={C. Stadelmann and W. Br{\"u}ck},
  journal={Neurological Sciences},
  • C. Stadelmann, W. Brück
  • Published 2004
  • Medicine
  • Neurological Sciences
  • Abstract.Multiple sclerosis (MS) is characterized by multiple demyelinated inflammatory lesions disseminated in the central nervous system (CNS). Additional features of MS pathology include axonal loss and gliosis. Remyelination may take place predominantly in the early stages of lesion formation. Pathologically, important inter-individual differences have been observed with respect to oligodendrocyte preservation. Furthermore, different mechanisms of demyelination, such as T-cell/macrophage… CONTINUE READING
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