Lessons from the genome sequence of Neurospora crassa: tracing the path from genomic blueprint to multicellular organism.

  title={Lessons from the genome sequence of Neurospora crassa: tracing the path from genomic blueprint to multicellular organism.},
  author={Katherine A Borkovich and Lisa A. Alex and Oded Yarden and Michael Freitag and Gloria Ellen Turner and Nick D Read and Stephan Seiler and Deborah Bell-Pedersen and John V. Paietta and Nora Plesofsky and Michael D Plamann and Marta Goodrich-Tanrikulu and Ulrich Schulte and Gertrud Mannhaupt and Frank E Nargang and Alan Radford and Claude P. Selitrennikoff and James E. Galagan and Jay C. Dunlap and Jennifer J. Loros and David E. A. Catcheside and Hirokazu Inoue and Rodolfo Aramayo and Michael Polymenis and Eric U Selker and Matthew S. Sachs and George A. Marzluf and Ian Paulsen and Rowland H. Davis and Daniel J Ebbole and Alex Zelter and Eric R Kalkman and Rebecca O'Rourke and Frederick James Bowring and Jane Yeadon and Chizu Ishii and Keiichiro Suzuki and Wataru Sakai and R. Brandon Pratt},
  journal={Microbiology and molecular biology reviews : MMBR},
  volume={68 1},
We present an analysis of over 1,100 of the approximately 10,000 predicted proteins encoded by the genome sequence of the filamentous fungus Neurospora crassa. Seven major areas of Neurospora genomics and biology are covered. First, the basic features of the genome, including the automated assembly, gene calls, and global gene analyses are summarized. The second section covers components of the centromere and kinetochore complexes, chromatin assembly and modification, and transcription and… CONTINUE READING
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