Lessons from studies on focal segmental glomerulosclerosis: an important role for parietal epithelial cells?

@article{Smeets2006LessonsFS,
  title={Lessons from studies on focal segmental glomerulosclerosis: an important role for parietal epithelial cells?},
  author={Bart Smeets and Henry B. P. M. Dijkman and Jack F. M. Wetzels and Eric J. Steenbergen},
  journal={The Journal of pathology},
  year={2006},
  volume={210 3},
  pages={263-72}
}
Glomerular diseases are caused by multiple mechanisms. Progressive glomerular injury is characterized by the development of segmental or global glomerulosclerosis independent of the nature of the underlying renal disease. Most studies on glomerular disease focus on the constituents of the filtration barrier (podocytes, glomerular basement membrane (GBM), endothelial cells) or the mesangial cells. Little attention is given to the epithelial cells lining Bowman's capsule, the so called parietal… CONTINUE READING

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