Lessons from animal models of vasculitis.

  title={Lessons from animal models of vasculitis.},
  author={I G Luzina and Barry S. Handwerger},
  journal={Current rheumatology reports},
  volume={2 5},
Vasculitis can occur as a primary disease or as a secondary manifestation of either another illness or a type-III hypersensitivity response to a foreign antigen. Over the past four decades, a number of animal models of vasculitis have been described. These models have served as important tools for enhancing our understanding of the basic mechanisms underlying the pathogenesis of vasculitis. In addition, animal models have made possible the preclinical testing of new therapeutic agents. Animal… CONTINUE READING