Corpus ID: 45400869

Lessons from animal models of arthritis.

  title={Lessons from animal models of arthritis.},
  author={W. B. van den Berg},
  journal={Current rheumatology reports},
  volume={4 3},
There is increasing thought that autoantibodies to systemic self-antigens may provide a principal effector mechanism for the initiation and propagation of joint inflammation. The recent identification of arthritis transfer with antibodies to the self-antigen glucose-6-phosphate isomerase has boosted this interest. Fc receptor involvement in arthritis has been evaluated, identifying pro-inflammatory and inhibitory Fc gamma receptor subtypes, and demonstrating a link between Fc gamma receptor… Expand
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