Lesions of the dorsomedial striatum delay spatial learning and render cue-based navigation inflexible in a water maze task in mice

Abstract

The dorsal striatum is involved in cue-based navigation strategies and in the development of habits. It has been proposed that striatum-dependent cued navigation competes with hippocampus-dependent spatial navigation in some circumstances. We have previously shown that large lesions of the dorsal striatum, as well as impairment of corticostriatal synaptic… (More)
DOI: 10.3389/fnbeh.2014.00042

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