Lesion size correlates with Leishmania antigen-stimulated TNF-levels in human cutaneous leishmaniasis.

@article{Oliveira2011LesionSC,
  title={Lesion size correlates with Leishmania antigen-stimulated TNF-levels in human cutaneous leishmaniasis.},
  author={Fabiano Oliveira and Andr{\'e} B{\'a}fica and Andrea B Rosato and Cec{\'i}lia Beatriz Fiuza Favali and Jackson Maur{\'i}cio Lopes Costa and Virginia Cafe and Manoel Barral-Netto and Aldina Barral},
  journal={The American journal of tropical medicine and hygiene},
  year={2011},
  volume={85 1},
  pages={70-3}
}
Cutaneous leishmaniasis (CL) is a worldwide disease endemic in several regions of the globe. The hallmark of CL is skin ulcers likely driven by efforts of the immune system to control Leishmania growth. Cytokines, such as tumor necrosis factor (TNF) and interferon-gamma can control disease progression in animal models. Nevertheless, the impact of these cytokines in CL ulcer outcome is not well established in humans. In this study, 96 CL patients from an endemic area of Leishmania braziliensis… CONTINUE READING

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