Lesion mapping of cognitive control and value-based decision making in the prefrontal cortex

@article{Glscher2012LesionMO,
  title={Lesion mapping of cognitive control and value-based decision making in the prefrontal cortex},
  author={Jan Gl{\"a}scher and Ralph Adolphs and Hanna Damasio and Antoine Bechara and David Rudrauf and Matthew R Calamia and Lynn K. Paul and Daniel Tranel},
  journal={Proceedings of the National Academy of Sciences},
  year={2012},
  volume={109},
  pages={14681 - 14686}
}
A considerable body of previous research on the prefrontal cortex (PFC) has helped characterize the regional specificity of various cognitive functions, such as cognitive control and decision making. Here we provide definitive findings on this topic, using a neuropsychological approach that takes advantage of a unique dataset accrued over several decades. We applied voxel-based lesion-symptom mapping in 344 individuals with focal lesions (165 involving the PFC) who had been tested on a… Expand

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