Lesion characterization in spectral photon-counting tomosynthesis

  title={Lesion characterization in spectral photon-counting tomosynthesis},
  author={Bj{\"o}rn Cederstr{\"o}m and Erik Fredenberg and Karl Berggren and Klaus Erhard and Mats Danielsson and Matthew G. Wallis},
  booktitle={Medical Imaging},
It has previously been shown that 2D spectral mammography can be used to discriminate between (likely benign) cystic and (potentially malignant) solid lesions in order to reduce unnecessary recalls in mammography. One limitation of the technique is, however, that the composition of overlapping tissue needs to be interpolated from a region surrounding the lesion. The purpose of this investigation was to demonstrate that lesion characterization can be done with spectral tomosynthesis, and to… 
Spectral image quality and applications in breast tomosynthesis
In the 1970s, it was determined that screening mammography is an efficient tool in fighting the increasing number of women dying from breast cancer, and many countries have established screening pr


Spectral lesion characterization on a photon-counting mammography system
Spectral X-ray imaging allows to differentiate between two given tissue types, provided their spectral absorption characteristics differ measurably. In mammography, this method is used clinically to
A Simulation Study on Spectral Lesion Characterization
A simulation study is presented to estimate the dependence of this spectral lesion characterization algorithm on various types of uncertainties including the biological variation of cyst fluid and tumor tissue, variations in the mammographic background texture, and errors in the spectral measurements.
Characterization of Cystic Lesions by Spectral Mammography: Results of a Clinical Pilot Study
Discriminating cystic from solid lesions with spectral mammography demonstrates promising results with the potential to reduce mammographic recalls and justifies undertaking a larger reader study to refine the algorithm and determine clinically relevant thresholds.
Measurement of breast-tissue x-ray attenuation by spectral mammography: solid lesions.
The separation between cyst-fluid and tumour attenuation was significant, which suggests it may be possible to distinguish cystic from solid breast lesions, and the results lay the groundwork for a clinical trial.
Measurement of breast-tissue x-ray attenuation by spectral mammography: first results on cyst fluid.
A method to measure x-ray attenuation of tissue samples using a prototype photon-counting spectral mammography unit, which proved stable between several measurements on the same sample and agreed within the precision of the elemental attenuation calculation over the mammographic energy range.
Short-term follow-up results in 795 nonpalpable probably benign lesions detected at screening mammography.
The benign nature of most nonpalpable probably benign lesions can be typified with short-term mammographic follow-up, and progression in the probably benign calcifications was usually unrelated to malignancy.
Energy-selective reconstructions in X-ray computerized tomography.
It is shown that for any material, complete energy spectral information may be summarized by a few constants which are independent of energy, and a technique is presented which uses simple, low-resolution, energy spectrum measurements and conventional computerized tomography techniques to calculate these constants.
Scatter rejection in multislit digital mammography.
The scatter to primary ratio (SPR) was measured on a scanning multislit full-field digital mammography system for different thickness of breast equivalent material and different tube voltages by using the scatter detective quantum efficiency.