Lesion associated expression of urokinase-type plasminogen activator receptor (uPAR, CD87) in human cerebral malaria

@article{Fauser2000LesionAE,
  title={Lesion associated expression of urokinase-type plasminogen activator receptor (uPAR, CD87) in human cerebral malaria},
  author={Susanne Fauser and Martin Deininger and Peter Gottfried Kremsner and Viktor Magdolen and Hermann Josef Schluesener},
  journal={Journal of Neuroimmunology},
  year={2000},
  volume={111},
  pages={234-240}
}
Blood-brain barrier disintegration and inflammatory cell recruitment are key processes in the pathogenesis of cerebral malaria (CM). Recent data provide convincing evidence that the serine protease urokinase-type plasminogen activator receptor (uPAR) is a key molecule in promoting cell adhesion and spreading. We have now analyzed expression of urokinase-type plasminogen activator receptor (uPAR, CD87), which is part of a cell surface associated proteolytic system, in brains of eight CM patients… CONTINUE READING

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