Lercanidipine, enalapril and their combination in the treatment of elderly hypertensive patients: placebo-controlled, randomized, crossover study with four ABPM

@article{Puig2007LercanidipineEA,
  title={Lercanidipine, enalapril and their combination in the treatment of elderly hypertensive patients: placebo-controlled, randomized, crossover study with four ABPM},
  author={Juan Garc{\'i}a Puig and Carlos Calvo and Olavi Luurila and Harri O Luurila and S Sulosaari and Arto Strandberg and Carlo Ghezzi},
  journal={Journal of Human Hypertension},
  year={2007},
  volume={21},
  pages={917-924}
}
This double-blind, placebo-controlled, four-way balanced design crossover study included hypertensive patients aged 60–85 years with mean office-measured sitting systolic blood pressure (SBP) 160–179 mm Hg and daytime SBP ⩾135 mm Hg. After a 2-week run-in period, during which previous medications were discontinued, each patient received the following four treatments in randomized order for 4 weeks each: lercanidipine 10 mg (L), enalapril 20 mg (E), lercanidipine 10 mg plus enalapril 20 mg (L/E… CONTINUE READING

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