Leptospirosis among hospitalized febrile patients in northern Tanzania.

  title={Leptospirosis among hospitalized febrile patients in northern Tanzania.},
  author={Holly M. Biggs and Duy M Bui and Renee Lynn Galloway and Robyn Anne Stoddard and Sean V Shadomy and Anne B. Morrissey and John A. Bartlett and Jecinta J Onyango and Venance Philis Maro and Grace Damas Kinabo and Wilbrod Saganda and John A Crump},
  journal={The American journal of tropical medicine and hygiene},
  volume={85 2},
We enrolled consecutive febrile admissions to two hospitals in Moshi, Tanzania. Confirmed leptospirosis was defined as a ≥ 4-fold increase in microscopic agglutination test (MAT) titer; probable leptospirosis as reciprocal MAT titer ≥ 800; and exposure to pathogenic leptospires as titer ≥ 100. Among 870 patients enrolled in the study, 453 (52.1%) had paired sera available, and 40 (8.8%) of these met the definition for confirmed leptospirosis. Of 832 patients with ≥ 1 serum sample available, 30… CONTINUE READING

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