Leptomeningeal metastases: analysis of 31 patients with sustained off-therapy response following combined-modality therapy.

@article{Siegal1994LeptomeningealMA,
  title={Leptomeningeal metastases: analysis of 31 patients with sustained off-therapy response following combined-modality therapy.},
  author={Tali Siegal and Alexander Lossos and Myer Raphael Pfeffer},
  journal={Neurology},
  year={1994},
  volume={44 8},
  pages={1463-9}
}
Thirty-one (23%) of 137 patients treated for leptomeningeal metastases (LM) achieved a sustained off-therapy response of at least 6 months' duration following treatment by a standard protocol. Of the 31 patients, equal distribution was found among various tumors: lymphoma, 13/44 (29%); breast carcinoma, 10/51 (20%); and other tumors, 8/42 (19%). Neuroimaging of the neuraxis disclosed subarachnoid deposits in 70%, with unexpected findings in 55%. At withdrawal of therapy, all 13 patients with… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 1 time. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 36 extracted citations

Leukemia and Lymphoma Metastases

View 4 Excerpts
Highly Influenced

Neoplastic meningitis.

The Lancet. Neurology • 2006
View 3 Excerpts
Highly Influenced

Practical aspects of the use of intrathecal chemotherapy.

Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria • 2017

Similar Papers

Loading similar papers…