Leptin stimulates pituitary prolactin release through an extracellular signal-regulated kinase-dependent pathway.

@article{Tipsmark2008LeptinSP,
  title={Leptin stimulates pituitary prolactin release through an extracellular signal-regulated kinase-dependent pathway.},
  author={Christian K Tipsmark and Christina N Strom and Sean T. Bailey and Russell John Borski},
  journal={The Journal of endocrinology},
  year={2008},
  volume={196 2},
  pages={
          275-81
        }
}
Leptin was initially identified as a regulator of appetite and weight control centers in the hypothalamus, but appears to be involved in a number of physiological processes. This study was carried out to examine the possible role of leptin in regulating prolactin (PRL) release using the teleost pituitary model system. This advantageous system allows isolation of a nearly pure population of lactotropes in their natural, in situ aggregated state. The rostral pars distalis were dissected from… CONTINUE READING
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