Leptin reverses sucrose-conditioned place preference in food-restricted rats.

@article{Figlewicz2001LeptinRS,
  title={Leptin reverses sucrose-conditioned place preference in food-restricted rats.},
  author={Dianne P. Figlewicz and Michael S. Higgins and S B Ng-Evans and P. Havel},
  journal={Physiology & behavior},
  year={2001},
  volume={73 1-2},
  pages={229-34}
}
Previous studies have suggested that food restriction can modify performance in the conditioned place preference (CPP) paradigm. In the present study, we tested the hypotheses that food restriction would enhance the development of a CPP to low-calorie sucrose pellets and that peripheral leptin replacement in food-restricted animals would reverse this effect. Using a range of 45-mg sucrose pellets (0-15 pellets) as a reward, we observed that a significant place preference was conditioned in food… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 49 extracted citations

Similar Papers

Loading similar papers…