Leptin levels in patients with anorexia nervosa are reduced in the acute stage and elevated upon short-term weight restoration

@article{Hebebrand1997LeptinLI,
  title={Leptin levels in patients with anorexia nervosa are reduced in the acute stage and elevated upon short-term weight restoration},
  author={Johannes Hebebrand and Werner Friedrich Blum and Nicola J Barth and Heinz Coners and Piera Englaro and Anders Juul and Andreas Ziegler and Andreas Warnke and Wolfgang Rascher and Helmut Remschmidt},
  journal={Molecular Psychiatry},
  year={1997},
  volume={2},
  pages={330-334}
}
Circulating leptin concentrations are known to be low in acute anorexia nervosa (AN), which is characterized by low weight, amenorrhea and specific psychopathological features. In this study plasma leptin concentrations were determined during inpatient treatment of 23 adolescent females with AN using a sensitive radioimmunoassay (RIA) and set into relationship to leptin levels of females matched for age, body mass index (BMI; kg m−2) and/or percent body fat. At referral patients had leptin… CONTINUE READING