Leptin-induced cardiac hypertrophy: RhoAing a lipid raft down a protective p38 MAPK signalling stream?

@article{Pemberton2008LeptininducedCH,
  title={Leptin-induced cardiac hypertrophy: RhoAing a lipid raft down a protective p38 MAPK signalling stream?},
  author={Christopher J. Pemberton},
  journal={Cardiovascular research},
  year={2008},
  volume={77 1},
  pages={4-5}
}
The 16-kDa peptide leptin has multiple physiological actions that affect satiety, energy expenditure, reproduction, immunity, and the cardiovascular system. These actions are mediated via the Ob-R receptor system, which has six isoforms (a–f) and are distributed widely throughout the body. The major contributor to circulating concentrations of leptin ( 5–15… CONTINUE READING