Leptin-induced adipose apoptosis: Implications for body weight regulation

Abstract

Great strides have been made in understanding the genetics of body weight regulation, in part due to the study of rodent models of obesity that are characterized by mutations affecting leptin or its receptors. Leptin, produced in adipose tissue, acts both centrally and peripherally to orchestrate complex metabolic and behavioral changes that increase loss… (More)
DOI: 10.1023/A:1024112716024

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