Leptin attenuates the anti-estrogen effect of tamoxifen in breast cancer.


BACKGROUND Leptin is a circulating peptide hormone, encoded by the obesity (ob) gene, acting as a regulator of food intake via hypothalamic-mediated effects. Recent studies have shown that leptin and leptin receptor (ObR) are involved in the carcinogenesis and development of breast cancer. In addition, functional cross talk between leptin and estrogen… (More)
DOI: 10.1016/j.biopha.2012.10.001


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@article{Chen2013LeptinAT, title={Leptin attenuates the anti-estrogen effect of tamoxifen in breast cancer.}, author={Xiaofeng Chen and Xiaoming Zha and Wei Chen and Tingting Zhu and Jinrong Qiu and O. D. R\oe and Jun Li and Zhaoxia Wang and Yongmei Yin}, journal={Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie}, year={2013}, volume={67 1}, pages={22-30} }