Leptin attenuates respiratory complications associated with the obese phenotype.

@article{Tankersley1998LeptinAR,
  title={Leptin attenuates respiratory complications associated with the obese phenotype.},
  author={Clarke G. Tankersley and Christopher O'donnell and Monica J. Daood and Jon F Watchko and Wayne Mitzner and Alan R. Schwartz and Paul R Smith},
  journal={Journal of applied physiology},
  year={1998},
  volume={85 6},
  pages={2261-9}
}
A profile of respiratory complications has been associated with the onset and development of obesity in humans. Similar phenotypes have been routinely demonstrated in genetic animal models of obesity such as the ob mouse (C57BL/6J-Lepob). The objective of the present study was to test the hypothesis that a constellation of respiratory complications are attenuated with leptin (i.e., protein product of the ob gene) replacement. Daily leptin administration during a 6-wk period was conducted to… CONTINUE READING
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