Leptin and the adaptations of lactation in rodents and ruminants.

  title={Leptin and the adaptations of lactation in rodents and ruminants.},
  author={Richard G. Vernon and Raphael G P Denis and Annette Sorensen and G. Ishmael Williams},
  journal={Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme},
  volume={34 11-12},
Lactation markedly increases nutrient requirements in both rodents and ruminants. This is met mostly by increased food intake, but there are also adaptations to increase metabolic efficiency. Despite such changes, lactating animals usually experience periods of negative energy balance. This is not due to a physical constraint on food intake, at least in the rat. Leptin, a hormone secreted by adipocytes, plays an important role in the regulation of appetite and energy balance. During lactation… CONTINUE READING


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