Leptin and reproduction: a review.

  title={Leptin and reproduction: a review.},
  author={Stergios J. Moschos and Jean L. Chan and Christos Socrates Mantzoros},
  journal={Fertility and sterility},
  volume={77 3},
OBJECTIVE To review recent advances in understanding the role of leptin in the physiology and pathophysiology of reproduction, with a focus on relevant clinical situations. DESIGN A MEDLINE computer search was performed to identify relevant articles. RESULT(S) Leptin, an adipocyte hormone important in regulating energy homeostasis, interacts with the reproductive axis at multiple sites, with stimulatory effects at the hypothalamus and pituitary and inhibitory actions at the gonads. More… CONTINUE READING
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