Leptin and other secretory products of adipocytes modulate multiple physiological functions.

@article{Weigle1997LeptinAO,
  title={Leptin and other secretory products of adipocytes modulate multiple physiological functions.},
  author={David S. Weigle},
  journal={Annales d'endocrinologie},
  year={1997},
  volume={58 2},
  pages={132-6}
}
The view that the adipocyte acts only as a passive storage site for energy in the form of triglyceride has been rendered obsolete by the discovery that adipocytes secrete a variety of metabolically active molecules. These molecules include free fatty acids, which decrease the rate of glucose oxidation by peripheral tissues; adipsin and other complement factors involved in host defense; tumor necrosis factor alpha, which may be an important determinant of insulin sensitivity; and angiotensinogen… CONTINUE READING

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