Leptin and its receptors are present in the rat olfactory mucosa and modulated by the nutritional status.

@article{Baly2007LeptinAI,
  title={Leptin and its receptors are present in the rat olfactory mucosa and modulated by the nutritional status.},
  author={Christine Baly and Josiane Aioun and Karine Badonnel and Marie-Christine Lacroix and Didier Durieux and Claire Schlegel and Roland Salesse and Monique Caillol},
  journal={Brain research},
  year={2007},
  volume={1129 1},
  pages={130-41}
}
Leptin is an adipocyte-derived cytokine that regulates body weight mainly via the long form of the leptin receptor (Ob-Rb). Leptin and its receptors are expressed in several tissues, suggesting that leptin might also be effective peripherally. We hypothesized that, as shown in taste cells, leptin and its receptors isoforms (Ob-Rs) could be present in the rat olfactory mucosa (OM). Using RT-PCR, light and electron microscopy immunohistochemistry (ICC), we found that different isoforms of the… CONTINUE READING