Leptin and biochemical markers of bone turnover in dialysis patients.

@article{Zoccali2004LeptinAB,
  title={Leptin and biochemical markers of bone turnover in dialysis patients.},
  author={Carmine Zoccali and Vincenzo Panuccio and Giovanni Tripepi and Sebastiano Cutrupi and Patrizia Pizzini and Francesca Mallamaci},
  journal={Journal of nephrology},
  year={2004},
  volume={17 2},
  pages={
          253-60
        }
}
BACKGROUND AND OBJECTIVE The adipose tissue cytokine leptin is suggested to interfere with bone turnover mechanisms because, in rats with leptin deficiency, intra-cerebroventricular administration of this cytokine causes a reduction in bone mass. We studied the relationship between plasma leptin and biochemical bone turnover indicators in 161 hemodialysis (HD) patients. RESULTS Plasma leptin was sex-dependent, being significantly higher (p<0.001 ) in female dialysis patients than in male… CONTINUE READING

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