Leptin and adipose tissue maldistribution in HIV-infected male patients with predominant fat loss treated with antiretroviral therapy.

@article{Estrada2002LeptinAA,
  title={Leptin and adipose tissue maldistribution in HIV-infected male patients with predominant fat loss treated with antiretroviral therapy.},
  author={Vicente Estrada and Manuel Serrano-R{\'i}os and Maria Teresa Mart{\'i}nez Larrad and Noemi G P Villar and Amparo Gonz{\'a}lez L{\'o}pez and Mar{\'i}a Jes{\'u}s T{\'e}llez and Cristina Fernandez},
  journal={Journal of acquired immune deficiency syndromes},
  year={2002},
  volume={29 1},
  pages={32-40}
}
BACKGROUND Metabolic disturbances and fat maldistribution are main features of the antiretroviral-related lipodystrophy syndrome (LDS). Different phenotypes of fat distribution abnormalities can be observed: fat loss, fat accumulation, or a mixed pattern. In patients with predominant loss of fat, the roles of leptin, lipids, and glucose homeostasis disturbances have not yet been clearly established. METHODS The study comprised 34 HIV-infected male patients receiving antiretroviral treatment… CONTINUE READING

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