Leptin and Mast Cells : A Novel Adipoimmune Link Short Report


and energy homeostasis, leptin, an adipokine (adipose tissue-secreted cytokine) (1,2), may also control lymphocyte and macrophage functions (3). However, until now, there is no published work, to our knowledge, about the possible role of leptin in the biology of mast cells (MCs). Here we report that an increased plasma level of leptin positively correlates with the number of adipose tissue MCs in patients with metabolic syndrome, a clinical disorder characterized by the clustering of atherogenic cardiovascular risk factors in one individual (4 and Refs therein).

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Cite this paper

@inproceedings{Ghenev2001LeptinAM, title={Leptin and Mast Cells : A Novel Adipoimmune Link Short Report}, author={Peter I. Ghenev and Marco Fiore and George Nikov Chaldakov}, year={2001} }